BEI Resources Science
The BEI Resources team of scientists has expertise in bacteriology, virology, protistology, toxins, and assay development. The scientific team provides a broad range of services to the scientific community to support research and development in new diagnostics, therapies, and vaccines to protect against infectious diseases.  

Below are numerous examples of the work we have performed and presented at national or international meetings.
Marco A. Riojas, Andrew M. Frank, Nikhita P. Puthuveetil, Beth Flores, Michael Parker, Stephen P. King, Malik Peiris, Daniel K. W. Chu, Briana Benton, Rebecca Bradford, Manzour Hernando Hazbón, Sujatha Rashid.  “A Rare Deletion in SARS-CoV-2 ORF6 Dramatically Alters the Predicted Three-Dimensional Structure of the Resultant Protein.”  bioRxiv.  June 9, 2020. 
NGS-Based Phylogenomic Analysis of Mycobacterium Type Strains Supports Reclassification of Many Species and Subspecies. Riojas MA, McGough K, Hazbón MH. Research Poster, Presented to the ASM Microbe Annual Meeting, 2017, New Orleans, LA.
Whole-Genome Sequencing and Phylogenomic Analysis of “Cryptic” Escherichia Strains Reveals Novel Species- and Subspecies-Level Clades. Riojas MA, Cantwell BJ, Hazbón MH. Research Poster, Presented to the ASM Microbe Annual Meeting, 2018, Atlanta, GA.
Development of droplet digital PCR for the detection of Babesia microti and Babesia duncani. Melisa Wilson, Kathleen C. Glaser, Debra Adams-Fish, Matthew Boley, Maria Mayda, and Robert E. Molestina*. BEI Resources, American Type Culture Collection, Manassas, Virginia 20110, USA

BEI Resources:  A Biological Resource Center for Parasitologists.  R.E. Molestina, Protistology Department, American Type Culture Collection, Manassas, Virginia, USA 2011
Effects of Toxoplasma gondii genotype and absence of host MAL/Myd88 on the temporal regulation of gene expression in infected microglial cells. K. C. Glaser, B. Hagos, and R. E. Molestina. BEI Resources/Protistology Department, American Type Culture Collection 2011

Assessment of cryoprotectant toxicity on the viability of Cryptosporidium parvum.  K. Glaser, B. Hagos, R. Molestina. 2011
Multiplex PCR for species-Level Identification of Bacillus anthracis and Detection of Plasmid Presence.  M. Riojas, Kathleen Stupec, Katalin Kiss. 2011
Production and Optimal Growth Conditions of Rickettsia Organisms. D.R. Merrill, B. Benton, D.N. Shahan, K. Langenbach, S. Radhakrishnan, R.O. Baker, 2009.
RT-PCR Subtyping of Influenza A Virus.T. Kelly, Y. Mehari, R. Taylor, K. Langenbach , R. Baker; BEI Resources, Manassas, VA, VCA Animal Hospital, Alexandria, VA, 2008.
Identify, Authenticate and Characterize Rickettsia prowazekii. Merrill, Bannon, Benton, Benson, Langenbach, Buck,Baker; BEI Resources, ATCC, Manassas VA, FBI, Quantico, VA, MRI, Frederick, MD, 2008.
Epsilon Toxin from C. perfringens: Characterization of Strain Genotype, Phenotype and Toxin Sensitive Cell Lines. M. S. Willis, L. Richardson, S. Fox, J. Sinclair, M.L. McKee; BEI Resources, ATCC, Manassas, VA., Uniformed Services University of the Health Sciences, Bethesda, MD, 2008.
Development and Optimization of a Yersinia pestis Plasmid Profiling Assay. J. Shifflett, K. J. Stupec, M. McKee, K. Langenbach, 2008.
Growth and Mutational Analysis of Dryvax® Virus on Bovine Cell Lines. Shahan, Evans, Langenbach, McArdle, Baker, 2008.
Authentication of Dengue Viruses using Reverse-Transcriptase Polymerase Chain Reaction. L. Taylor, Y. Mehari, R. Taylor,R. O. Baker; BEI Resources, Manassas, VA, VCA Animal Hospital, Alexandria, VA, 2008.
Evaluation of Various Buffer Systems for Long-Term Storage of Active Ricin Toxin. J. Sinclair, A. Sohrabi, M. Willis, A. D. O'Brien, M. McKee; USUHS, Bethesda, MD, BEI Resources, ATCC, Manassas, VA, 2008.
Utilization of qPCR for Rapid Characterization and Authentication of Large and Diverse Rickettsia Collections. B. Benton, D. Merrill, R. O. Baker, S. Radhakrishnan, Kurt J. Langenbach, 2008.

Long-Term and Short-Term Stability of Viruses Depend on Storage Temperature and Preservation. D R. Merrill, C D. Wade, P Fahnestock, R.O. Baker.


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