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NR-36167   Monoclonal Anti-Hantaan Virus Gc Glycoprotein, Clone 8E10 (produced in vitro)
(Monoclonal Antibodies)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Description: Monoclonal Anti-Hantaan Virus Gc Glycoprotein, Clone 8E10 (produced in vitro)
Organism: Hantaan virus
Biosafety Level: 1
Availability Status: In Stock
Store at: -20°C or colder
Contributor: CS Schmaljohn
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Antibody Class: IgG1κ
Mouse monoclonal antibody prepared against the Hantaan virus Gc (formerly G2) glycoprotein was affinity purified from clone 8E10 hybridoma supernatant using protein G magnetic beads. The B cell hybridoma was generated by the fusion of Sp2/0-Ag14 mouse myeloma cells with splenocytes from mice immunized with protein A sepharose-bound Hantaan virus glycoprotein-antibody complexes as described by Arikawa et al.

This reagent is part of the Joel M. Dalrymple - Clarence J. Peters USAMRIID Antibody Collection.

Each vial of NR-36167 contains approximately 100 µL of purified monoclonal antibody in PBS.

NR-36167 is reactive in indirect immunofluorescence assays using Vero E6 cells infected with Hantaan virus. Although clone 8E10 is reported to lack neutralizing activity against Hantaan virus, NR-36167 is somewhat active in plaque reduction neutralization tests. The antibody is also reported to function in ELISA, hemagglutination inhibition, and immunoprecipitation assays and to cross-react on Prospect Hill virus, Puumala virus, and Sapporo rat virus.
Citations: Acknowledgment for publications should read "The following reagent was obtained from the Joel M. Dalrymple - Clarence J. Peters USAMRIID Antibody Collection through BEI Resources, NIAID, NIH: Monoclonal Anti-Hantaan Virus Gc Glycoprotein, Clone 8E10 (produced in vitro), NR-36167."
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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