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BEI Resources currently limits the total number of "Made to Order" items which can be ordered by a registrant to 10 "Made to Order" items per 6 month period. Please check the Availability Status on the items you are ordering and limit orders appropriately.
NR-21961   Schistosoma mansoni, Strain PR-1 Exposed Biomphalaria glabrata, Strain M-Line
(Parasitic Worms)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Designations: Schistosoma mansoni, Strain PR-1 Exposed Biomphalaria glabrata, Strain M-Line
Organism: Schistosoma mansoni
Biosafety Level: 2
Availability Status: In Stock
Store at: 26°C to 28°C in suitable aquaria
Contributor: FA Lewis
Quantity limit per year for this item is 3,000 snails. Orders over this limit will be sent to NIAID for approval before shipment.

Schistosoma mansoni (S. mansoni), strain PR-1 was collected from infected snails in Arecibo, Puerto Rico in 1950.

S. mansoni, strain PR-1 is maintained in the M-line strain of Biomphalaria glabrata (B. glabrata). The M-line strain is descended from a cross between a S. mansoni resistant albino strain of B. glabrata, collected in Brazil, and a S. mansoni susceptible pigmented strain of B. glabrata, collected in Puerto Rico in 1944.

Strain PR-1 was maintained by NIH/NIAID until 1978, when it was brought to the Biomedical Research Institute.

NR-21961 consists of up to 100 B. glabrata, strain M-line, infected with S. mansoni, strain PR-1, in a petri dish.

Note: Infected snails are exposed to miracidia only a few days before shipment. Laboratories should be aware and take caution of possible cercarial exposure following a 4 week prepatent period after exposure to miracidia (depending on the temperature and species). BEI Resources recommends consulting personnel in your institution's Occupational Safety and Health office for clearance to receive and maintain the infected snails.

Shipments of snails ordered through BEI Resources will be shipped by Biomedical Research Institute in Rockville, MD. To set up a standing recurring order of snails or mice, please use the form linked here: Schistosome Standing Order Reagent Request Form. The form can be submitted via email to

Note: The approximate time required to fill orders of 200 or more exposed B. glabrata snails is 2 to 3 months.
Citations: Acknowledgment for publications should read "The following reagent was provided by the NIAID Schistosomiasis Resource Center for distribution through BEI Resources, NIAID, NIH: Schistosoma mansoni, Strain PR-1 Exposed Biomphalaria glabrata, Strain M-Line, NR-21961."
Publications Citing
this Reagent:
Ahmad G., et al. "Protective and Antifecundity Effects of Sm-p80 Based DNA Vaccine Formulation Against Schistosoma mansoni in a Nonhuman Primate Model." Vaccine 27 (2009): 2830-2837. PubMed: 19366570.

Ahmad G., et al. "Preclinical Prophylactic Efficacy Testing of Sm-p80 Based Vaccine in a Nonhuman Primate Model of Schistosoma mansoni and IgG/IgE Responses to Sm-p80 in Human Sera from Schistosome Endemic Area." J.Infect. Dis. 204 (2011): 1437-1449. PubMed: 21921206.

Ahmad G., et al. "Prime-Boost and Recombinant Protein Vaccination Strategies Using Sm-p80 Protects Against Schistosoma mansoni Infection in the Mouse Model to Levels Previously Attainable Only by the Irradiated Cercarial Vaccine." Parasitol. Res. 105 (2009): 1767-1777. PubMed: 19809833.

Ahmad G., et al. "Sm-p80 Based DNA Vaccine Formulation Induces Potent Protective Immunity Against Schistosoma mansoni." Parasite Immunol. 31 (2009): 156-161. PubMed: 19222788.

Shollenberger, L. M., et al. "HIV-1 Vaccine-Specific Responses Induced by Listeria Vector Vaccines are Maintained in Mice Subsequently Infected with a Model Helminth Parasite, Schistosoma mansoni." Vaccine 31 (2013): 5651-5658. PubMed: 19222788.
For a list of permits that may be required for shipping this product and to set the permit information preferences; please select a country from the drop down below.

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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BEI Resources products are intended for laboratory research purposes only. They are not intended for use in humans.

While BEI Resources uses reasonable efforts to include accurate and up-to-date information on this site, BEI Resources makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. BEI Resources does not warrant that such information has been confirmed to be accurate.

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