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BEI Resources currently limits the total number of "Made to Order" items which can be ordered by a registrant to 10 "Made to Order" items per 6 month period. Please check the Availability Status on the items you are ordering and limit orders appropriately.
NR-21962   Schistosoma mansoni, Strain NMRI Exposed Biomphalaria glabrata, Strain NMRI
(Parasitic Worms)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Designations: Schistosoma mansoni, Strain NMRI Exposed Biomphalaria glabrata, Strain NMRI
Organism: Schistosoma mansoni
Biosafety Level: 2
Availability Status: In Stock
Store at: 26°C to 28°C in suitable aquaria
Contributor: FA Lewis
Quantity limit per year for this item is 6,000 snails. Orders over this limit will be sent to NIAID for approval before shipment.

Schistosoma mansoni (S. mansoni), strain NMRI was isolated in the 1940s from S. mansoni eggs obtained from infected Puerto Rican school children.

S. mansoni, strain NMRI is maintained in the NMRI strain of Biomphalaria glabrata (B. glabrata). B. glabrata, strain NMRI snail host is an albino snail that is highly susceptible to the NMRI strain of S. mansoni. It was derived from a cross between pigmented Puerto Rican (susceptible) snails and Newton's M-line snails.

NR-21962 consists of up to 100 B. glabrata, strain NMRI, infected with S. mansoni, strain NMRI, in a petri dish.

Note: Infected snails are exposed to miracidia only a few days before shipment. Laboratories should be aware and take caution of possible cercarial exposure following a 4 week prepatent period after exposure to miracidia (depending on the temperature and species). BEI Resources recommends consulting personnel in your institution's Occupational Safety and Health office for clearance to receive and maintain the infected snails.

Depending on the species requested, orders can usually be filled between 1-3 weeks. Shipments of snails ordered through BEI Resources will be shipped by Biomedical Research Institute in Rockville, MD. To set up a standing recurring order of snails or mice, please use the form linked here: Schistosome Standing Order Reagent Request Form. The form can be submitted via email to

Note: The approximate time required to fill orders of 300 or more B. glabrata snails is 4 to 8 weeks.
Citations: Acknowledgment for publications should read "The following reagent was provided by the NIAID Schistosomiasis Resource Center for distribution through BEI Resources, NIAID, NIH: Schistosoma mansoni, Strain NMRI Exposed Biomphalaria glabrata, Strain NMRI, NR-21962."
Publications Citing
this Reagent:
Ahmad G., et al. "Protective Effects of Sm-p80 in the Presence of Resiquimod as an Adjuvant Against Challenge Infection with Schistosoma mansoni in Mice." Int. J. Infect. Dis. 14 (2010): 781-787. PubMed: 20630783.

Da'dara, A. A., et al. "Schistosome Tegumental Ecto-Apyrase (SmATPDase1) Degrades Exogenous Pro-Inflammatory and Pro-Thrombotic Nucleotides." Peer J. 2 (2014): e316. PubMed: 24711968.

Da'dara, A. A., et al. "Schistosome apyrase SmATPDase1, but not SmATPDase2, Hydrolyses Exogenous ATP and ADP." Purinergic Signalling (2014): 1-8. PubMed: 24894599.

El-Shehabi, F., et al. "SA Novel G Protein-Coupled Receptor of Schistosoma mansoni (SmGPR-3) is Activated by Dopamine and is Widely Expressed in the Nervous System." PLoS Negl.Trop. Dis. 6 (2012): e1523. PubMed: 22389736.

Lee, V. S. T., et al. "Schistosoma mansoni: Assessment of Effects of Oleic Acid, Cercarial Age and Water Temperature on Parasite-Host Attraction." Int. J. Parasitol. 43 (2013): 837-842. PubMed: 23770037.

Luyai, A. E., et al. "Differential Expression of Anti-Glycan Antibodies in Schistosome-Infected Humans, Rhesus Monkeys and Mice." Glycobiology 24 (2014): 602-618. PubMed: 24727442.

MacDonald, K., et al. "Functional Characterization of a Novel Family of Acetylcholine-Gated Chloride Channels in Schistosoma mansoni." PLoS Pathog. 10 (2014): e1004181. PubMed: 24945827.

Patocka, N. and P. Ribeiro. "The Functional Role of a Serotonin Transporter in Schistosoma mansoni Elucidated through Immunolocalization and RNA Interference (RNAi)." Mol. Biochem. Parasit. 187 (2013): 32-42. PubMed: 23246818.

Patocka, N., et al. "Serotonin Signaling in Schistosoma mansoni: A Serotonin?Activated G Protein-Coupled Receptor Controls Parasite Movement." PLoS Pathog. 10 (2014): e1003878. PubMed: 24453972.

Prasanphanich, N. S., et al. "Immunization with Recombinantly Expressed Glycan Antigens from Schistosoma mansoni Induces Glycan-Specific Antibodies against the Parasite." Glycobiology 24 (2014): 619-637. PubMed: 24727440.

Taman, A., and P. Ribeiro. "Characterization of a Truncated Metabotropic Glutamate Receptor in a Primitive Metazoan, the Parasitic Flatworm Schistosoma mansoni." PloS One 6 (2011): e27119. PubMed: 22069494.

Torben W., et al. "Role of Antibodies in Sm-p80-Mediated Protection against Schistosoma mansoni Challenge Infection in Murine and Nonhuman Primate Models." Vaccine 29 (2011): 2262-2271. PubMed: 23000221.

Zhang W., et al. "Sm-p80 Based DNA Vaccine Provides Baboons with Levels of Protection against Schistosoma mansoni Infection Comparable to Those Achieved by the Irradiated Cercarial Vaccine." J. Infect. Dis. 201 (2010): 1105-1112. PubMed: 20187746.

Zhang W., et al. "Sm-p80-Based DNA Vaccine Made in a Human Use Approved Vector VR1020 Protects against Challenge Infection with Schistosoma mansoni in Mouse." Parasite Immunol. 32 (2010): 252-258. PubMed: 20398225.

Zhang W., et al. "Schistosoma mansoni Antigen Sm-p80: Prophylactic Efficacy of a Vaccine Formulated in Human Approved Plasmid Vector and Adjuvant (VR1020 and alum)." Acta Trop. 118 (2011): 142-151. PubMed: 21334302.

Zhao, J., et al. "T Cell Responses are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice." J. Virol. 84 (2010): 9318-9325. PubMed: 20610717.
For a list of permits that may be required for shipping this product and to set the permit information preferences; please select a country from the drop down below.

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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BEI Resources products are intended for laboratory research purposes only. They are not intended for use in humans.

While BEI Resources uses reasonable efforts to include accurate and up-to-date information on this site, BEI Resources makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. BEI Resources does not warrant that such information has been confirmed to be accurate.

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