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Room temperature, protected from moisture
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
ARP-3420 [human immunodeficiency virus 1 (HIV-1) NL4-3 heat stable antigen reporter vector (HIV-1 pNL4-3.HSA.R+E-)] contains a 5' frameshift mutation which render this NL4-3 clone env-. Murine heat stable antigen CD24 (HSA) gene was inserted into the pNL4-3 (BEI Resources ARP-114) nef gene to produce this clone. This construct is 14,973 base pairs including the insert. pNL4-3.HSA.R+E- is ampicillin resistant. For additional details please refer to the provided protocol, vector maps and sequence files.
Each vial of ARP-3420 contains approximately 5 µg of dried purified DNA stabilized in DNAstable®PLUS. Please refer to the appropriate data sheet for lot-specific information.
He, J., et al. “Human Immunodeficiency Virus Type 1 Viral Protein R (Vpr) Arrests Cells in The G2 Phase of the Cell Cycle by Inhibiting P34cdc2 Activity.” J Virol. 69 (1995): 6705-6711. PubMed: 7474080.
Connor, R. I., et al. “Vpr is Required for Efficient Replication of Human Immunodeficiency Virus Type-1 in Mononuclear Phagocytes.” Virology 206 (1995):935-944. PubMed: 7531918.
Patent pending. Requests from commercial organizations must be directed to the New York University Office of Industrial Liaison at the following email address: sadhana.chitale@nyumc.org..
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