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NR-31065   Filamentous Hemagglutinin (FHA) from Bordetella pertussis
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Description: Filamentous Hemagglutinin (FHA) from Bordetella pertussis
Organism: Bordetella pertussis
Biosafety Level: 1
Availability Status: Discontinued (Please See Comments)
Store at: 2°C to 8°C
Contributor: BEI Resources
NR-31065, Filamentous Hemagglutinin (FHA) from Bordetella pertussis, is no longer available.

Filamentous hemagglutinin adhesin (FHA) was purified from Bordetella pertussis (B. pertussis) by conventional chromatography.

FHA is a major virulence factor involved in adhesion and spread of B. pertussis throughout the respiratory tract. Studies with FHA-deficient B. pertussis strains have implicated FHA in tracheal colonization, cell adherence, and invasion of macrophages and epithelial cells. FHA is a component of several of the acellular pertussis vaccines licensed for use in the U.S.

Each vial of NR-31065 contains 50 µg of lyophilized FHA. When reconstituted with 0.5 mL of molecular grade water, the concentration of buffer is 50 mM Tris-HCl (pH 8.0), 500 mM NaCl and 1.25% trehalose.
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Filamentous Hemagglutinin (FHA) from Bordetella pertussis, NR-31065."
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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