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NR-51702   Fluzone® Quadrivalent Influenza Vaccine, 2018-2019 Formula
(Vaccines)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Description: Fluzone® Quadrivalent Influenza Vaccine, 2018-2019 Formula
Organism: Influenza A & B viruses
Biosafety Level: 1
Availability Status: In Stock
Store at: 2°C to 8°C
Contributor: NIAID/NIH
Comments:
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

NR-51702 is an inactivated influenza virus vaccine prepared from influenza viruses propagated in embryonated chicken eggs. The virus-containing allantoic fluid was harvested and inactivated with formaldehyde. Influenza virus was concentrated and purified in a linear sucrose density gradient solution using a continuous flow centrifuge. The virus was then chemically disrupted using a non-ionic surfactant, octylphenol ethoxylate (Triton® X-100) producing a “split virus.” The split virus was further purified and then suspended in sodium phosphate-buffered isotonic sodium chloride solution. The Fluzone® Quadrivalent process uses an additional concentration factor after the ultrafiltration step in order to obtain a higher hemagglutinin (HA) antigen concentration.

The hemagglutinin content was standardized according to U.S. Public Health Service requirements. Each 0.5 mL syringe contains the recommended ratio of 15 µg each of the HA antigens from influenza viruses A/Michigan/45/2015 X-275 (H1N1), A/Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2), B/Phuket/3073/2013 (B Yamagata lineage) and B/Maryland/15/2016 BX-69A (a B/Colorado/6/2017-like virus, B Victoria lineage). No thimerosal or any other preservative was used in the manufacturing process of the single-dose presentations of Fluzone® vaccine.

Please note that this vaccine preparation is being released for research use only and not for human use. Vaccines produced for the 2018-2019 season are now past their expiration dates (EXP. 30JUN19).

Each syringe contains 0.5 mL of split-virus vaccine in phosphate-buffered saline.
Citations: Acknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: Fluzone® Quadrivalent Influenza Vaccine, 2018-2019 Formula, NR-51702.”
PERMITS
For a list of permits that may be required for shipping this product and to set the permit information preferences; please select a country from the drop down below.

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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BEI Resources products are intended for laboratory research purposes only. They are not intended for use in humans.

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