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NR-3573  Influenza A virus, Kilbourne F34: A/Texas/36/1991 (HA) x A/equine/Prague/1/1956 (NA) x A/Puerto Rico/8/1934 (H1N7)
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Description: Kilbourne F34: A/Texas/36/1991 (HA) x A/equine/Prague/1/1956 (NA) x A/Puerto Rico/8/1934 (H1N7)
Organism: Influenza A virus
Biosafety Level: 2
Availability Status: In Stock
Store at: -60°C or colder
Contributor: NIAID/NIH
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

NR-3573 is an antigenic hybrid reassortant virus that carries the H1 hemagglutinin (HA) of influenza A virus, A/Texas/36/1991 (H1N1) and the N7 neuraminidase (NA) of influenza A virus, A/equine/Prague/1/1956 (H7N7). The direct antecedents of NR-3573 are both reassortant influenza viruses. Reassortant X-113 (Kilbourne F76; BEI Resources NR-3579) is A/Texas/36/1991 (HA, NA) x A/Puerto Rico/8/1934 (H1N1). The H7N7(R) parent (Kilbourne F58; BEI Resources NR-3649) is a high yield reassortant that carries the HA and NA genes of A/equine/Prague/1/1956 (H7N7). It was derived from six different influenza strains through nine rounds of reassortment and selection. Nucleotide sequencing at BEI Resources of a portion of the matrix (M) gene (RNA 7) from NR-3573 indicates that the M gene is derived from A/Puerto Rico/8/1934 (H1N1). The five genes encoding the remaining internal proteins and the nonstructural protein may be derived from any of A/Bangkok/1/1979 (H3N2), A/Brazil/11/1978 (H1N1), A/England/42/1972 (H3N2), A/Puerto Rico/8/1934 (H1N1), A/Texas/36/1991 (H1N1), or A/equine/Prague/1/1956 (H7N7).

Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant influenza A virus, A/Texas/36/1991 (HA) x A/equine/Prague/1/1956 (NA) x A/Puerto Rico/8/1934 (H1N7).

Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F34 information

Download (Word Docs):Detailed Description
File Number:F34
Virus Name:
Virus Attributes:Type A Virus. reassortant. animal virus - human virus hybrids. antigenic (HA/NA) hybrid . human HA-specific antigenic hybrid
AntiserumImmunizing VirusLocationAntiserum Attributes
15002A/Texas/36/91 - A/Equi/Prague/1/56 (H1N7)C60antigenic (HA/NA) hybrid. HA Specific,
15003A/Texas/36/91 - A/Equi/Prague/1/56 (H1N7)C61antigenic (HA/NA) hybrid. HA Specific,
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Kilbourne F34: A/Texas/36/1991 (HA) x A/equine/Prague/1/1956 (NA) x A/Puerto Rico/8/1934 (H1N7), NR-3573."
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.
  • USDA APHIS VS 16-6 or 16-6A permit must be obtained and a copy of the permit must be sent to ATCC in advance of shipment. The Application Form VS 16-3 (Import controlled material import or transport organisms or vectors) must be submitted to USDA APHIS Veterinary Services to obtain the VS 16-6 or 16-6A permit.

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