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BEI Resources currently limits the total number of "Made to Order" items which can be ordered by a registrant to 10 "Made to Order" items per 6 month period. Please check the Availability Status on the items you are ordering and limit orders appropriately.
NR-48813  Human coronavirus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), Recombinant Infectious Clone with ORF5 Red Fluorescent Protein Replacement (icMERS-CoV-RFP-ΔORF5)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Description: Middle East Respiratory Syndrome Coronavirus (MERS-CoV), Recombinant Infectious Clone with ORF5 Red Fluorescent Protein Replacement (icMERS-CoV-RFP-ΔORF5)
Organism: Human coronavirus
Biosafety Level: 3+
Availability Status: In Stock
Store at: -60°C or colder
Contributor: RS Baric
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Recombinant infectious clone with ORF5 red fluorescent protein replacement (icMERS-CoV-RFP-ΔORF5).

NR-48813 is an engineered recombinant coronavirus based on the MERS-CoV, EMC2012 genome. The group-specific MERS-CoV accessory gene ORF5 was deleted and replaced with a synthetic gene encoding red fluorescent protein. The individual MERS-CoV group-specific ORFs are not essential for virus replication, although the absence of these genes as a group does attenuate peak viral titers. The MERS-CoV ORF5 accessory protein was recently shown to be a potent interferon antagonist.

ATCC ® employs Biosafety Level 3 facilities with enhanced practices and procedures for research and production activities utilizing genetically modified MERS coronaviruses.

Each vial contains approximately 1 mL of cell lysate and supernatant from Cercopithecus aethiops kidney epithelial cells (Vero: ATCC ® CCL-81™) infected with icMERS-CoV-RFP-ΔORF5.

Additional information and tools are available at ViPR (Virus Pathogen Resource).

Use of this material for any purpose by commercial or for profit entities requires a license from The University of North Carolina at Chapel Hill prior to shipment. For more information on obtaining a license to use this material please contact the UNC-CH Office of Technology Development, 100 Europa Drive, Suite 430, Chapel Hill, North Carolina 27517, Phone (919) 966-3929, Email:
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Middle East Respiratory Syndrome Coronavirus, Recombinant Infectious Clone with ORF5 Red Fluorescent Protein Replacement (icMERS-CoV-RFP-ΔORF5), NR-48813."
For a list of permits that may be required for shipping this product and to set the permit information preferences; please select a country from the drop down below.

  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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