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NR-45926  Staphylococcus aureus, SA LinR #14
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Staphylococcus aureus
Designations: SA LinR #14
Biosafety Level: 2
Availability Status: In Stock
Store at: -60°C or colder
Contributor: MJ Ferraro
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Staphylococcus aureus (S. aureus), strain SA LinR #14 (also referred to as NRS121) was isolated in 2001 from an 85-year-old male with dialysis-associated peritonitis in Massachusetts, USA.

S. aureus, strain SA LinR #14 is a methicillin-resistant S. aureus (MRSA) strain. It was deposited as resistant to linezolid; positive for mec (subtype IV); MLST sequence type (ST) 507; eGenomic spa type 7, eGenomic spa repeats YHGCMBQBLO; Ridom spa type t064. S. aureus, strain SA LinR #14 was co-isolated with SA LinR #12 (NRS119) and SA LinR #13 (NRS120) from the first clinically reported case of a MRSA infection that demonstrated resistance to linezolid. Based on pulsed-field gel electrophoresis, SA LinR #12 and SA LinR #13 are identical and SA LinR #14 is closely related to both. While each strain has a different antibiogram, all three are resistant to linezolid due to a G2576T mutation in domain V in one or more 23S rRNA genes (Escherichia coli numbering).

Each vial contains approximately 0.5 mL of bacterial culture in Tryptic Soy broth supplemented with 10% glycerol.
Citations: Acknowledgment for publications should read "The following reagent was provided by the Network on Antimicrobial Resistance in Staphylococcus aureus (NARSA) for distribution by BEI Resources, NIAID, NIH: Staphylococcus aureus, Strain SA LinR #14, NR-45926."
Additional Information: NARSA NRS121
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