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BEI Resources currently limits the total number of "Made to Order" items which can be ordered by a registrant to 10 "Made to Order" items per 6 month period. Please check the Availability Status on the items you are ordering and limit orders appropriately.
NR-46062  Staphylococcus aureus, H2138 (Isolate 10)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Staphylococcus aureus
Designations: H2138 (Isolate 10)
Biosafety Level: 2
Availability Status: In Stock
Store at: -60°C or colder
Contributor: P Wilson
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Staphylococcus aureus (S. aureus), strain H2138, isolate 10 (also referred to as NRS271) was isolated in 2002 from a wound drain site of 52-year-old male in the United Kingdom.

S. aureus, strain H2138 (Isolate 10) is a linezolid-resistant S. aureus (LRSA), methicillin-resistant S. aureus (MRSA) strain and is the second clinically isolated linezolid-resistant MRSA strain. It was deposited as resistant to linezolid, tedizolid, ciprofloxacin, oxacillin and penicillin; intermediate resistance to erythromycin; positive for mec (subtype IV); MLST sequence type (ST) 22; eGenomic spa type 382, eGenomic spa repeats TJJEJNF2MNF2MOMOKR; Ridom spa type t032; phage type E-MRSA 15. S. aureus, strain H2138 (Isolate 10) developed from a linezolid susceptible strain during treatment. It is reported to have a G2576T mutation in domain V of the 23s rRNA gene (Escherichia coli numbering) and a Q3K mutation in the L3 ribosomal protein.

Each vial contains approximately 0.5 mL of bacterial culture in Tryptic Soy broth supplemented with 10% glycerol.
Citations: Acknowledgment for publications should read "The following reagent was provided by the Network on Antimicrobial Resistance in Staphylococcus aureus (NARSA) for distribution by BEI Resources, NIAID, NIH: Staphylococcus aureus, Strain H2138 (Isolate 10), NR-46062."
Additional Information: NARSA NRS271
Publications Citing
this Reagent:
Silva-Del Toro, S. L., K. E. Greenwood-Quaintance, and R. Patel. "In vitro Activity of Tedizolid Against Linezolid-Resistant Staphylococci and Enterococci." Diagn.Microbiol. Infect. Dis. S0732-8893 (2016): 30009-8. PubMed: 26971179.
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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