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NR-46177  Staphylococcus aureus, CA-347
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Staphylococcus aureus
Designations: CA-347
Biosafety Level: 2
Availability Status: In Stock
Store at: -60°C or colder
Contributor: CDC
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Staphylococcus aureus (S. aureus), strain CA-347 (also referred to as NRS648) was isolated in December 2005 from the blood of a 57-year-old male in California, USA.

S. aureus, strain CA-347 is a methicillin-resistant S. aureus (MRSA) strain. Strain CA-347 was deposited as positive for mec (subtype II); negative for PVL and tsst; pulsed-field type USA600. S. aureus, strain CA-347 is a USA600 representative isolate. USA600 isolates have the same MLST profile (ST 45), SCCmec (subtype II or IV) and spa repeats (A2AKEEMBKB) and resistant to erthromycin and clindamycin. Isolates are predominantly found in nares of healthy individuals and in bloodstream infections. These isolates are associated with a higher rate of clinical failure and mortality, particularly those with a heterogeneous vancomycin-intermediate S. aureus (hVISA) phenotype. While USA600 isolates are uncommon in the United States, the clonally-related Berlin strain is widespread throughout Germany, the Netherlands, and Ontario, Cananda. The complete genome sequence of S. aurues, strain CA-347 is available (Genbank: CP006044).

Each vial contains approximately 0.5 mL of bacterial culture in Tryptic Soy broth supplemented with 10% glycerol.

Note: If homogeneity is required for your intended use, please purify prior to initiating work.
Citations: Acknowledgment for publications should read "The following reagent was provided by the Network on Antimicrobial Resistance in Staphylococcus aureus (NARSA) for distribution by BEI Resources, NIAID, NIH: Staphylococcus aureus, Strain CA-347, NR-46177."
Additional Information: NARSA NRS648
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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