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NR-53726 Cercopithecus aethiops, African Green Monkey Kidney Epithelial Cells (Vero E6) Expressing High Endogenous Angiotensin-Converting Enzyme 2
(Cell Banks)

Price: All BEI Resources products are provided
at no cost to registered researchers.

Description:

African Green Monkey Kidney Epithelial Cells (Vero E6) Expressing High Endogenous Angiotensin-Converting Enzyme 2

Organism:

Cercopithecus aethiops

Biosafety Level:

Availability Status:

In Stock

Store at:

-100°C or colder, preferably in the vapor phase of a liquid nitrogen freezer

Contributor:

R Baric

Comments:

Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

NR-53726 consists of a preparation of African green monkey (Cercopithecus aethiops) kidney epithelial cells (Vero E6) expressing high endogenous angiotensin-converting enzyme 2 (ACE2). This cell line was obtained by sorting Vero E6 cells for cells expressing high levels of endogenous ACE2.

ACE2 is an enzyme established as the functional receptor by which SARS-Related Coronavirus 2 (SARS-CoV-2) enters host target cells. The SARS-CoV-2 spike glycoprotein mediates viral binding to the host ACE2 receptor. This protein forms a trimer, and when bound to ACE2, allows fusion of the viral and cellular membranes, allowing viral entry and replication. The interaction of ACE2 and the spike glycoprotein during viral infection is currently under study.

Each vial contains approximately 1 mL of cell culture suspension frozen in cell growth medium (90%) and DMSO (10%) cryopreservative. Sufficient cells are provided to initiate at least one new culture.

Citations:

Acknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: African Green Monkey Kidney Epithelial Cells (Vero E6) Expressing High Endogenous Angiotensin-Converting Enzyme 2, NR-53726."

Restrictions On Use:

This material is distributed for internal research, noncommercial purposes only. This material, its product or its derivatives may not be distributed to third parties. Except as performed under a U.S. Government contract, individuals contemplating commercial use of the material, its products or its derivatives must contact the contributor to negotiate a license. U.S. Government contractors may need a license before first commercial sale.

Product Name:

African Green Monkey Kidney Epithelial Cells (Vero E6) Expressing High Endogenous Angiotensin-Converting Enzyme 2

Disclaimers:

You are authorized to use this product for research use only. It is not intended for human use.

Use of this product is subject to the terms and conditions of the BEI Resources Material Transfer Agreement (MTA). The MTA is available on our Web site at www.beiresources.org.

While BEI Resources uses reasonable efforts to include accurate and up-to-date information on this product sheet, neither ATCC^® nor the U.S. Government makes any warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. Neither ATCC^® nor the U.S. Government warrants that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, use and disposal. ATCC^® and the U.S. Government are not liable for any damages or injuries arising from receipt and/ or use of this product. While reasonable effort is made to ensure authenticity and reliability of materials on deposit, the U.S. Government, ATCC^®, their suppliers and contributors to BEI Resources are not liable for damages arising from the misidentification or misrepresentation of products.

Citation:

Biosafety Level:

1 Appropriate safety procedures should always be used with this material. Laboratory safety is discussed in the following publication: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, and National Institutes of Health. Biosafety in Microbiological and Biomedical Laboratories (BMBL). Current Edition. Washington, DC: U.S. Government Printing Office.

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Notices and Disclaimers

BEI Resources products are intended for laboratory research purposes only. They are not intended for use in humans.

While BEI Resources uses reasonable efforts to include accurate and up-to-date information on this site, BEI Resources makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. BEI Resources does not warrant that such information has been confirmed to be accurate.

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Product Highlights for NR-53726

Product Sheet Information for NR-53726 Cercopithecus aethiops, African Green Monkey Kidney Epithelial Cells (Vero E6) Expressing High Endogenous Angiotensin-Converting Enzyme 2, For research use only. Not for use in humans.

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