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Clostridium perfringens (C. perfringens) perfringolysin O is a thiol-activated cytolysin that binds to membrane cholesterol and forms oligomeric pores, causing membrane damage.NR-10357 is a recombinant form of perfringolysin O from C. perfringens. The recombinant protein was cloned from ATCC ® 13124™ and contains an N-terminal histidine tag. NR-10357 was expressed in Escherichia coli and purified using standard chromatographic methods. NR-10357 has been qualified for western blots and cytolytic assays.Each vial of NR-10357 contains approximately 25 µg of perfringolysin O in 50 mM HEPES (pH 8.0) containing 10% glycerol, 150 mM NaCl and 5 mM DTT.
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biological materials provided by BEI Resources, please select this link: Compliance Requirements.
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