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Extremely toxic - any exposure may be fatal! Exercise caution! Do not lyophilize!Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.NR-742 was
isolated from Ricinus communis (R. communis) seeds and purified by ion
exchange chromatography. The signal sequence was cleaved from the protein and
the expected molecular weight is 60.2 kDa.
sequence for the R. communis gene for
the ricin toxin precursor protein has been reported (GenBank: XP_002534649).
is a glycoprotein isolated from the seeds of R. communis, the castor bean plant. Ricin toxin consists of two polypeptide
chains, A and B, linked by a disulfide bond.
The A chain catalytically inactivates the eukaryotic 28S ribosomal RNA
subunit, resulting in the inhibition of protein synthesis and death of the
cell. The B chain is responsible for
receptor binding and delivery of the toxin to the target cell.
Each vial of NR-742 contains approximately 1 mg of ricin toxin suspended in phosphate buffered saline (PBS).
For information about toxin amounts excluded from CDC Select Agent regulations, click here.
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Do NOT reference BEI Resources or ATCC Catalog Numbers in the Material Description
fields found on the permits and/or forms.
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as they appear on your BEI Resources registration.
Information about permits is provided as a courtesy to BEI Resources customers.
While we use reasonable efforts to include accurate and up-to-date information on
this page, we make no warranties or representation as to its accuracy.
For more information on the necessary compliance requirements associated with the
biological materials provided by BEI Resources, please select this link: Compliance Requirements.
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