TARGET Research Results
Details
DescriptionPPE FAMILY PROTEIN
Accession numberRv1387
Gene namePPE20
Gene length1620
Protein length539
Coordinates1561769..1563388
Orientation+
Molecular mass55403.42
Isoelectric point4.48

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1387-55[no data]
JHU1387-367[no data]
JHU1387-321[no data]
JHU1387-368[no data]
 

CDC1551 Homolog
ORFMT1431
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1387-367MT1431Rv13873671620yes
JHU1387-321MT1431Rv13873211620no (will be available later)
JHU1387-368MT1431Rv13873681620yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]