TARGET Research Results
Details
DescriptionPUTATIVE METHYLTRANSFERASE
Accession numberRv1405c
Gene nameRv1405c
Gene length825
Protein length274
Coordinates1581145..1581969
Orientation-
Molecular mass29262.18
Isoelectric point4.43

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1405c-796[no data]
JHU1405c-767[no data]
JHU1405c-795[no data]
JHU1405c-76[no data]
 

CDC1551 Homolog
ORFMT1449
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1405c-796MT1449Rv1405c796825no (will be available later)
JHU1405c-767MT1449Rv1405c767825yes
JHU1405c-795MT1449Rv1405c795825no (will be available later)
JHU1405c-76MT1449Rv1405c76825yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]