TARGET Research Results
Details
DescriptionPROBABLE EXCINUCLEASE ABC (SUBUNIT B - HELICASE) UVRB
Accession numberRv1633
Gene nameuvrB
Gene length2097
Protein length698
Coordinates1837075..1839171
Orientation+
Molecular mass78038.1
Isoelectric point4.79

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1633-565[no data]
JHU1633-589[no data]
JHU1633-800[no data]
 

CDC1551 Homolog
ORFMT1669
Essentiality Prediction
Sassetti et al, 2003*non-essential

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1633-565MT1669Rv16335652220no (will be available later)
JHU1633-589MT1669Rv16335892220no (will be available later)
JHU1633-800MT1669Rv16338002220yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]