TARGET Research Results
Details
DescriptionPPE FAMILY PROTEIN
Accession numberRv1808
Gene namePPE32
Gene length1230
Protein length409
Coordinates2049921..2051150
Orientation+
Molecular mass39899.16
Isoelectric point4.09

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1808-828[no data]
JHU1808-385[no data]
JHU1808-386[no data]
JHU1808-737Not-Attenuated
 

CDC1551 Homolog
ORFMT1856.1
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1808-828MT1856.1Rv18088281161no (will be available later)
JHU1808-385MT1856.1Rv18083851161no (will be available later)
JHU1808-386MT1856.1Rv18083861161yes
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]