TARGET Research Results
Details
DescriptionPROBABLE CUTINASE PRECURSOR CFP21
Accession numberRv1984c
Gene namecfp21
Gene length654
Protein length217
Coordinates2227908..2228561
Orientation-
Molecular mass21782.3
Isoelectric point5.88

Database Crossreferences
Deletion Mutant Phenotype
in-vivoguinea pig
 mouse
 rabbit

in-vitroHBMEC
 macrophage

Mutant Survival in DeADMAn (Lamichhane et al., 2005)*

Strain NamePhenotype (Mouse)
JHU1984c-506[no data]
JHU1984c-514[no data]
JHU1984c-548[no data]
JHU1984c-508[no data]
 

CDC1551 Homolog
ORFMT2037
Essentiality Prediction
Sassetti et al, 2003*[no data]

JHU Transposon Mutant(s) Available
NameMT#Rv#POIGene LengthAvailable from BEI
JHU1984c-506MT2037Rv1984c506654yes
JHU1984c-514MT2037Rv1984c514654no (will be available later)
JHU1984c-548MT2037Rv1984c548654no (will be available later)
JHU1984c-508MT2037Rv1984c508654no (will be available later)
  
For a list of currently available mutants, please visit BEI's transposon mutant webpage.

If we have not disrupted your gene using random mutagenesis, we may be able to create a knockout mutant for you.

References
Lamichhane, G., M. Zignol, N. J. Blades, D. E. Geiman, A. Dougherty, J. Grosset, K. W. Broman, and W. R. Bishai. (2003) Proc. Natl. Acad. Sci. USA 100:7213-7218. [Abstract/Free Full Text]
Sassetti, C. M., Boyd, D. H. & Rubin, E. J. (2003) Proc. Natl. Acad. Sci. USA 100:12989-12994. [Abstract/Free Full Text]
Lamichhane G, Tyagi S, Bishai WR (2005) Infect Immun. Apr;73(4):2533-40.
[Abstract/Free Full Text]