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NR-4  Escherichia coli, H10407 (Serotype O78:H11)
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at no cost to registered researchers.
Organism: Escherichia coli
Designations: H10407 (Serotype O78:H11)
Biosafety Level: 2
Availability Status: In Stock
Store at: -60°C or colder
Contributor: ATCC®
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

Escherichia coli (E.coli), strain H10407 was isolated from human feces.

Escherichia coli, strain H10407 was deposited at ATCC ® in the early 1980s by Samuel B. Formal, Department of Bacterial Diseases, Walter Reed Army Institute of Research, Washington, DC.

The enterotoxigenic Escherichia coli (E. coli; ETEC), strain H10407 was isolated from a patient with diarrhea in Bangladesh. It produces at least two types of virulence factors: 1) colonization factor antigen I (CFA/I), which is responsible for adhesion of bacterial cells to intestinal epithelial cells, and 2) heat-labile (LT) and heat-stable (ST) enterotoxins which cause diarrhea. E. coli H10407 carries three plasmid species: 1) pCS1 (CFA/I+ST+; 95,000 bp), 2) pJY11 (LT+ST+; 65,000 bp), and 3) pTRA1 (65,000 bp), a self-transmissible plasmid which mobilizes pCS1 and pJY11. The gene for another heat-stable enterotoxin (EAST1) has been found in E. coli H10407, sequenced (GenBank: AB042004), and reported to have enterotoxin activity.

Each vial contains approximately 0.5 mL of bacterial culture in 0.5X Tryptic Soy Broth supplemented with 10% glycerol.
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Escherichia coli, Strain H10407, NR-4."
Publications Citing
this Reagent:
Wang, F. "Development and Application of Serogroup-independent and Serogroup-specific Loop-mediated Isothermal Amplification Assays for Detecting Shiga Toxin-Producing Escherichia coli." Diss. China Agricultural University, 2011.
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

Derived from:  ATCC 35401
Genomic DNA from Escherichia coli, Strain H10407
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