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NR-20804   Mycobacterium leprae, Phthiocerol Dimycocerosate (PDIM)
(Antigen Preparations)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Mycobacterium leprae
Description: Mycobacterium leprae, Phthiocerol Dimycocerosate (PDIM)
Biosafety Level: 1
Availability Status: Discontinued (Please See Comments)
Store at: Room temperature
Contributor: NIH - Leprosy Research Support Contract
Comments:
NR-20804, Mycobacterium leprae, Phthiocerol Dimycocerosate, is no longer available.

NR-20804 is a preparation of phthiocerol dimycocerosate (PDIM) derived from the total cellular lipids of Mycobacterium leprae (M. leprae) extracted from a pool of infected armadillo liver and spleen tissue. PDIM is a virulence lipid found within the extracellular peribacillary substance, spherical droplets, and capsular materials unique to M. leprae and has been isolated in large quantities from infected armadillo tissue.

Each vial contains approximately 250 µg of dried PDIM pooled from up to three different strains of M. leprae. Please refer to the Certificate of Analysis for information regarding the specific strains used in the production of each lot.

Note: PDIM is soluble in chloroform:methanol (2:1). Chloroform or DMSO can also be used depending on the downstream application.
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Mycobacterium leprae, Phthiocerol Dimycocerosate, NR-20804."
PERMITS
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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