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NR-14844   Mycobacterium tuberculosis, Strain H37Rv, Purified Trehalose Dimycolate (TDM)
(Antigen Preparations)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Mycobacterium tuberculosis
Description: Mycobacterium tuberculosis, Strain H37Rv, Purified Trehalose Dimycolate (TDM)
Biosafety Level: 1
Availability Status: Temporarily Out of Stock (Please See Comments)
Store at: -80°C or colder
Contributor: BEI Resources or NIH - TB Vaccine Testing and Research Materials Contract
Comments:

Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

This item is currently in our production queue. Please allow ample time for distribution lots to be made available.


NR-14844 is a preparation of purified trehalose dimycolate (TDM) that was extracted from the lipid fraction obtained from irradiated Mycobacterium tuberculosis, strain H37Rv cells. Following purification steps, the TDM was dried under nitrogen gas.


Each vial contains approximately 250 µg of dried, purified TDM from M. tuberculosis, strain H37Rv.

Note: TDM is soluble in chloroform:methanol (2:1). DMSO can also be used depending on the downstream application.

Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Mycobacterium tuberculosis, Strain H37Rv, Purified Trehalose Dimycolate (TDM), NR-14844."
Publications Citing
this Reagent:
Reyes, F., et al. "Immunogenicity and Cross-Reactivity against Mycobacterium tuberculosis of Proteoliposomes Derived from Mycobacterium bovis BCG." BMC Immunol. 14 (2013): S7. PubMed: 23458692.

Nouailles, G., et al. "CXCL5-Secreting Pulmonary Epithelial Cells Drive Destructive Neutrophilic Inflammation in Tuberculosis." J. Clin. Invest. 124 (2014): 1268-1282. PubMed: 24509076.

Rodriguez, M. E., et al. "Mycobacterial Phosphatidylinositol Mannoside 6 (PIM6) Up-Regulates TCR-Triggered HIV-1 Replication in CD4+ T Cells." PLoS One 8 (2013): e80938. PubMed: 24282561.
PERMITS
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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BEI Resources products are intended for laboratory research purposes only. They are not intended for use in humans.

While BEI Resources uses reasonable efforts to include accurate and up-to-date information on this site, BEI Resources makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. BEI Resources does not warrant that such information has been confirmed to be accurate.


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