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BEI Resources currently limits the total number of "Made to Order" items which can be ordered by a registrant to 10 "Made to Order" items per 6 month period. Please check the Availability Status on the items you are ordering and limit orders appropriately.
NR-19342   Mycobacterium leprae, Phenolic Glycolipid-I (PGL-I)
(Antigen Preparations)
Price: All BEI Resources products are provided
at no cost to registered researchers.
Organism: Mycobacterium leprae
Description: Mycobacterium leprae, Phenolic Glycolipid-I (PGL-I)
Biosafety Level: 1
Availability Status: Temporarily Out of Stock (Please See Comments)
Store at: Room temperature
Contributor: BEI Resources or NIH - TB Vaccine Testing and Research Materials Contract
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.

This item is currently in our production queue. Please allow ample time for distribution lots to be made available.

NR-19342 is a preparation of the phenolic glycolipid-1 (PGL-I) of Mycobacterium leprae (M. leprae) extracted from infected armadillo liver and spleen tissue. Crude lipids were obtained from chloroform:methanol (2:1) extraction of tissues and eluted on a silica gel column followed by preparative thin layer chromatography. The fractions containing PGL-I were pooled in chloroform:methanol (2:1) and dried under a nitrogen bath.

Each vial contains approximately 1 mg of dried PGL-1 from M. leprae.

Note: PGL-1 can be reconstituted in methanol or ethanol.

Note: PGL-I has a glassy appearance and can be difficult to observe in the glass vial.
Citations: Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Mycobacterium leprae Phenolic Glycolipid-I (PGL-I), NR-19342."
Publications Citing
this Reagent:
Medeiros, M. F., et al. "An Attempt to Improve Pure Neural Leprosy Diagnosis Using Immunohistochemistry Tests in Peripheral Nerve Biopsy Specimens." Appl. Immunohistochem. Mol. Morphol. 22 (2014): 222-230. PubMed: 23702646.

Sakamuri, R. M., et al. "Detection of Stealthy Small Amphiphilic Biomarkers." J. Microbiol. Methods 103 (2014): 112-117. PubMed: 24880131.

Spencer, J. S., and P. J. Brennan. "The Role of Mycobacterium leprae Phenolic Glycolipid I (PGL-I) in Serodiagnosis and in the Pathogenesis of Leprosy." Lepr. Rev. 82 (2011): 344. PubMed: 22439275.
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  • Customers located in the state of Hawaii will need to contact the Hawaii Department of Agriculture to determine if an Import Permit is required. A copy of the permit or documentation that a permit is not required must be sent to ATCC in advance of shipment.

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