At BEI Resources, we're the leading source for high quality cultures and reagents for microbiology and infectious diseases research. As you explore the benefits we offer, you will see how BEI Resources can serve as a catalyst for your research efforts worldwide.  BEI Resources materials are provided at no cost to registered researchers (additional shipping charges may apply).

We'll take care of the details - so you can focus on your research.

HIV-1 transmitted/founder (T/F) viruses represent the initial viral strains that establish infection following transmission and play a crucial role in understanding HIV pathogenesis. These viruses provide invaluable insights into the early immune evasion strategies employed by HIV, guiding the development of therapeutic interventions to enhance host immune responses.

Toxoplasma gondii, the causal agent of toxoplasmosis, is an ideal model system to study the basic biology of parasitism. Recent additions to the BEI Resources protozoan catalog include two bioluminescent transgenic T. gondii reporter strains derived from the type I strain RH (NR-59752) and the type II strain ME49 (NR-59751).

Reporter virus particles (RVPs) are non replicative, virus like particles engineered to display the authentic surface (envelope) proteins of pathogenic viruses while carrying a modified genome that cannot replicate. They are antigenically equivalent to live virus at the level of viral entry but are replication incompetent and safe to use at BSL 2, eliminating the need for high containment facilities or propagation of infectious virus.

For more than a century, research on Treponema pallidum (T. pallidum), the causative agent of syphilis and other treponemal diseases, has been limited by the organism’s resistance to traditional laboratory cultivation. Recent advances in in vitro cultivation have begun to change that landscape. Building on these breakthroughs, BEI Resources is pleased to announce the availability of three newly added Treponema pallidum strains.

Monkeypox virus (MPXV), scientifically classified as Orthopoxvirus monkeypox, is a double-stranded enveloped DNA virus and a member of the Orthopoxvirus genus of the Poxviridae family. MPXV is divided into two distinct genetic clades: clade I, previously referred to as the Congo Basin or Central African clade, which includes sub-clades Ia and Ib; and clade II, formerly known as the West African clade, comprising sub-clades IIa and IIb.

Trypanosoma cruzi is the causative agent of Chagas disease, a major public health problem in Latin America and an emergent disease in the US. There is no vaccine available, and drugs are limited with severe side effects. Efforts to generate new therapies are affected by limitations in the understanding of parasite biology and disease pathogenesis.

Candida auris is an emerging multidrug-resistant pathogenic yeast that causes invasive infections and outbreaks in nosocomial settings, resulting in high mortality. First identified in 2009, this pathogen has now been isolated in over sixty countries across six continents. Unlike other Candida species, C. auris demonstrates a unique ability to colonize the skin, persist on surfaces for prolonged periods, and spread efficiently within healthcare facilities.

The NIAID Data Ecosystem Discovery Portal (https://data.niaid.nih.gov/) allows researchers to search simultaneously across millions of publicly available datasets to find infectious and immune-mediated disease data for reanalysis and accelerates the work of researchers, leading to faster development of diagnostics, therapeutics, and vaccines.

The Discovery Portal can be used to:

• Search across repositories to quickly find datasets that you didn’t know were available to bring other dimensions into your analyses.
• Track research across funding programs or specific scientific areas.

Vector-borne microbial pathogens have evolved a series of strategies to evade the immune system and establish infections in the mammalian host. In this setting, BEI Resources functions as a centralized bioresource for accessibility of reference strains of arthropod vectors to the global public health scientific community. The BEI Vector Resources program currently provides over 60 colonies of live mosquitoes as well as Ixodid and soft ticks, sandflies, black flies    and triatomines. 

Now available Mpox virus, isolate hMPXV/USA/MA001/2022 (NR-58622), from the current outbreak. For a complete listing of available of Mpox reagents and other Orthopox virus related reagents, click here.

BEI Resources is continually building a comprehensive repository of microbiological and emerging disease related organisms and reagents. Suggestions for materials to be added to our repository are always welcome. Click here to tell us what you don't see in our catalog!